Posts Tagged ‘depression’

Depression Breakthrough? The Many Faces of “Special K”

Recently, a 45-year-old anesthetic drug has been getting attention as a remarkably effective antidepressant. Ketamine is used for anesthesia in children as well as adults and animals, and sometimes for relief of chronic pain. It’s considered very safe. But it’s also known as Special K among people who use it as a hallucinogenic club drug. What makes ketamine special in mental illness is that it is the first truly new potential drug treatment in more than 50 years. Exploratory studies going back 13 years have suggested that ketamine has some unique effects in people with depression, both unipolar major depressive disorder and bipolar depression. So, what’s the big deal? First, ketamine acts fast. Unlike most current antidepressants on the market, which can take 6-8 weeks to work, ketamine shows antidepressant effects within 24 hours, sometimes in just a couple of hours. Second, ketamine works in people with treatment-resistant depression. A […]

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Depression Hits Close to Home

By Audra Moran My name is Audra Moran, and I am a founding board member of Cure Alliance for Mental Illness. I spent the early part of my career working in mental illness—first as a rehabilitation counselor and later in research funding, at the Brain and Behavior Research Foundation, where I was Vice President for Development and Scientific Affairs. All of which is to say that I am no stranger to psychiatric brain disorders. So when my father, at age 60, experienced his first episode of major depression, I should have been prepared, but instead felt immobilized. What should or could I do to help, especially from so far away? I was in New York, he was home in central Florida. My first attempt to help didn’t go so well—a clinician I located in his area began my father on a course of antipsychotics, though his depression did not have […]

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